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41. All of the following are typically associated with loss of 40% of the circulating blood volume except_______________?

A. A decrease in the blood pressure
B. A decrease in the central venous pressure
C. A decrease in the heart rate
D. A decrease in the urine output

42. Edema is due to_______________?

A. Increased albumin in blood and decreased globin
B. Decreased albumin conc. in blood
C. Increased osmotic pressure
D. None of the above

43. A 20 year male complains of recurrent attacks of sore tthroat since 2 years. The total leukocyte count was 1000/ul. A differential count revealed severe neutropenia. The diagnosis is________________?

A. Subleukemic leukemia
B. Infectious mononucleosis
C. Agraulocytosis
D. Leukoerythroblastic anemia

44. Thrombocytopenia due to increased platelet destruction is seen in_________________?

A. Aplasti anemia
B. Cancer chemotherapy
C. Acute leukemia
D. Systemic lupus erythematosus

45. Primary hemostasis is disturbed in______________?

A. Platelet disorder
B. Lupus anticoagulant
C. Hemophilia
D. Liver disease

46. A 3-year old child presented with progressive anaemia, jaundice & failure to thrive. O/E: pallor, splenomegaly are seen Peripheral smear showed normoblasts and small round intensely stained red cells. The likely diagnosis is________________?

A. Here ditary spherocytosis
B. Thalassaemia
C. Sickle cell anaemia
D. Vitamin B12 deficiency anaemia

47. Increased levels of haemoglobin A2 is characteristic of________________?

A. Sickle cell trait
B. b-thalassaemia crait
C. Glucose-6 phosphate dehydrogenase deficiency
D. a-Thalassamia

48. In sickle cell anaemia there is_____________?

A. 75 to 100% haemoglobins
B. 10 to 20% haemoglobins
C. 20 to 30% haemoglobins
D. 50 to 60% haemoglobins

49. The fading of cellular chromatin is_____________?

A. Karyolysis
B. Karyorrhexis
C. Pyknosis
D. Cytolysis

50. Auto immune hymolytic anemia is seen in_______________?

A. AML
B. CML
C. CLL
D. ALL