**Question 101:**
**Aminocaproic acid is a drug of choice for the treatment of:**
– A) Acute myocardial infarction
– **B) Bleeding from fibrinolytic therapy**
– C) Heart failure
– D) Multiple pulmonary emboli

**Question 102:**
**Tick the drug type for which microsomal oxidation is the most prominent:**
– **A) Lipid soluble**
– B) Water soluble
– C) Low molecular weight
– D) High molecular weight

**Question 103:**
**Tick the feature of the sublingual route:**
– **A) Pretty fast absorption**
– B) A drug is exposed to gastric secretion
– C) A drug is exposed to more prominent liver metabolism
– D) A drug can be administrated in a variety of doses

**Question 104:**
**Which of the following statements concerning potassium channel openers is true?**
– A) These agents decrease transmembrane calcium current associated in smooth muscle with long-lasting relaxation and in cardiac muscle with a reduction in contractility
– B) These agents have a moderate reflex and vascular dilative action caused by the stimulation of sensitive nerve endings
– C) Beneficial effects of these agents are related primarily to their hemodynamic effects – decreased heart rate, blood pressure, and contractility – which decrease myocardial oxygen requirements at rest and during exercise
– **D) These agents increase the permeability of K channels, probably ATP-dependent K channels, that results in stabilizing the membrane potential of excitable cells near the resting potential**

**Question 105:**
**This drug reduces blood pressure by acting on vasomotor centers in the CNS:**
– A) Labetalol
– **B) Clonidine**
– C) Enalapril
– D) Nifedipine

**Question 106:**
**Indomethacin is preferred over Colchicine for Acute Attack of Gout because it is:**
– A) Less likely to cause gastrointestinal bleeding.
– **B) Less likely to cause diarrhea.**
– C) Less likely to cause acute renal failure.
– D) More likely to reduce inflammation.
– E) More likely to prevent further acute attacks

**Question 107:**
**With prolonged use in seizure states, which of the following drugs can cause coarsening of facial features, hirsutism, gingival hyperplasia, and osteomalacia?**
– A) Valproic acid.
– B) Carbamazepine.
– C) Ethosuximide.
– **D) Phenytoin**

**Question 108:**
**Cardiac Toxicity is a common side effect seen with:**
– A) Bleomycin
– **B) Doxorubicin**
– C) Captopril
– D) Prazosin

**Question 109:**
**Only Aspirin can:**
– A) Reduce fever.
– **B) Irreversibly inhibit its target enzyme.**
– C) Prevent episodes of gouty arthritis with long-term use.
– D) Reduce the risk of colon cancer.

**Question 110:**
**Which of the following drugs when used for a prolonged period in the maintenance treatment of tonic-clonic seizures can lead to increased metabolism of warfarin-like drugs?**
– **A) Phenobarbital.**
– B) Meprobamate
– C) Chlordiazepoxide
– D) Triazolam
– E) Zolpidem